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Actos after two years, at higher doses, doubles the risk of bladder cancer

Filed June 4th, 2012 Laurie

Taking the top-selling Type 2 diabetes drug Actos for more than two years doubles the risk of developing bladder cancer.

Since Actos supplanted Avandia as the top-selling drug for regulating blood glucose levels in Type 2 diabetics, more studies have been completed highlighting the dangers of the drug, studies which could have been overlooked had it still trailed in sales behind the previous top-seller. Chief among those dangers is that of bladder cancer. There have been several lawsuits already filed against the makers of Actos on behalf of people who’ve developed the life-threatening disease while taking the drug.

In the latest study, according to a report, researchers at Lady Davis Institute of Jewish General Hospital in Montreal, Quebec, have noticed that patients taking Actos for longer than two years double their chance they’ll develop bladder cancer. Taking the drug, the researchers note, increases a person’s chance of developing bladder cancer by 83 percent. That risk increases the longer a patient takes the drug and with higher doses.

The Food and Drug Administration recently issued a drug safety alert to this danger but those who’ve filed lawsuits against Takeda Pharmaceuticals, the makers of Actos, claim they were never warned about this danger.

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