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Blood Pressure, Bleeding Risks Linked to Cancer Drug Avastin

Filed September 19th, 2013 Joshua Sophy

New research has identified a heightened risk of high blood pressure and severe bleeding episodes associated with the cancer drug Avastin.

The study was conducted at Changhai Hospital, China. The research team was examining the risks associated with the use of Avastin (bevacizumab) when it was used in treating colorectal cancer. The study notes that some recent studies have suggested that Avastin use is beneficial for people suffering from colorectal cancer.

Researchers included nearly 7,000 participants in 15 different clinical trials before publishing their study in the journal Clinical Drug Investigation. The results showed that Avastin was linked to a three-times greater risk of high blood pressure and a twofold risk of severe gastrointestinal bleeding and hemorrhaging, the study notes.

Avastin has benefits for people suffering from advanced colorectal cancer but also the risks of high blood pressure and gastrointestinal bleeding, the study found.

We’ve reported on the adverse effects of taking Avastin numerous times in the past. In fact, in December 2010, the U.S. Food and Drug Administration (FDA) said that it would work to remove breast cancer as one of Avastin’s approved indications.

In addition to the risks highlighted in this most recent study, previous research conducted on the drug’s safety shows that Avastin has been linked to blindness, perforations in the nose, stomach and intestines, heart attack and heart failure, and stroke.

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