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DMAA Study A Blow to “Natural” Claims

Filed June 29th, 2012 Laurie

A new analysis says controversial substance known as DMAA is not detectable in plant material and oil from geraniums. The analysis is being called the “final coffin nail in the long suffering DMAA debate.”

DMAA is typically found in body-building and weight loss supplements. The synthetic substance can cause heart attacks by elevating blood pressure in users. Forty-two public complaints have been lodged about products containing DMAA linking it to side effects of the nervous system, psychiatric disorders, and death.

There has been considerable controversy surrounding DMAA and whether or not it is in fact a constituent of geranium. It was first manufactured synthetically by Eli Lilly in the 1940s.

The analysis was published Monday in the Journal of Analytical Toxicology. The authors report that gas chromatography – mass spectrometry (LC-MS-MS) analysis of geranium oils of young and mature, fresh and dried leaves and stems found no detectable trace of DMAA.

When scientists subjected three commercially supplements to containing DMAA/MHA to the same analytical procedures, they concluded that the amounts of MHA measured “were incompatible with the use of reasonable amounts of P. graveolens extract or concentrate, suggesting MHA was of synthetic origin.”

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