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FDA Issues Strong Magnesium Sulfate Warnings About Stopping Pre-Term Labor

Filed May 31st, 2013 Laurie

Magnesium sulfate injections should not be used for more than five to seven days to stop pre-term labor in pregnant women, according to a new safety communication issued by the U.S. Food and Drug Administration (FDA).

Administering magnesium sulfate for longer than that span can result in low calcium levels and bone problems in the developing baby or fetus, including fractures. The minimum amount of time in which injections can be administered without harming the baby is unknown.

Magnesium sulfate is approved by the FDA to prevent seizures during preeclampsia, a condition in which the pregnant woman develops high blood pressure and protein in the urine, and for control of seizures during eclampsia. Use of the injections to stop pre-term labor in pregnant women is an off-label use of the drug.

 

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