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FDA: Hepatitis C Drug May Cause Deadly Skin Rash

Filed December 20th, 2012 Laurie

The U.S. Food and Drug Administration (FDA) warned this week that hepatitis C drug, Incivek, can cause a serious and potentially fatal skin rash.

Invicek is most commonly used with peginterferon alfa and ribavirin to treat genotype 1 chronic hepatitis C in adults with severely damaged livers, including those with cirrhosis, who have previously received interferon-based treatment. Many of the patients who reported the skin rash continued to take the drugs, even as their condition worsened.

The agency urged people taking the combination therapy to stop the drugs immediately and seek medical attention if they develop a skin condition. The FDA also noted that the rash should be considered a side effect of the drug treatment. Patients who reported developing the rash all had to be hospitalized. The FDA said it will add a new boxed warning–the agency’s most serious–about the skin condition risk to the Invicek drug label.

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