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Kidney Problems may be Associated with Popular Heartburn Drugs

Filed January 18th, 2016 admin

A study involving heartburn sufferers and their medications has revealed a possible connection to an increased risk in kidney disease. Previous studies had linked the use of heartburn medications with increases in bone fractures, pneumonia, and a potentially serious infection known as Chlostridium difficile.

This study involved 10,482 patients and was conducted for over 13 years. Researchers monitored patients taking proton pump inhibitor (PPI); PPIs include Nexium, Prilosec, and Prevacid. The New York Times wrote that patients taking non-PPI medications, known as H2 receptor antagonists, including Pepcid, Zantac, and Tagamet were also studied. The research appeared in the American Medical Association journal, JAMA Internal Medicine.

The group of patients taking PPIs experienced a 20 to 50 percent greater increased risk of developing chronic kidney disease. The non-PPI group taking H2 receptor antagonists did not experience this increased risk, according to The New York Times. Dr. Morgan E. Grams, a Johns Hopkins kidney specialist, noted that, while all medicines have side effects, kidney function should be monitored in patients using a PPI medication for any long period of time.

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