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Report: Propecia Potentially Linked to Permanent Sexual Side Effects

Filed February 8th, 2013 admin

Sexual side effects endured by men taking the hair-loss medication, Propecia, may be permanent, according to a new report.

QuarterWatch cited evidence in the U.S. Food and Drug Administration (FDA) Adverse Event Report System (FAERS) of a risk of persistent sexual side effects from the drug finasteride, which is sold under the brand names Propecia and Proscar. Evidence is now emerging that the sexual side effects of Propecia can sometimes be irreversible and were most notable in younger men taking Propecia for male pattern baldness,” QuarterWatch said.

The study, which was conducted by the Institute for Safe Medication Practices (ISMP), looked at 50,289 reports of fatal, disabling or other serious injury received by the FAERS during the second quarter of 2012, QuarterWatch said. It found that 46 of the 61 serious adverse event reports for Propecia in the second quarter highlighted a sexual problem. In 20 of those cases, the reports indicated a significant or persistent disability. Reduced sexual drive and dysfunction were the most frequent side effects reported in pre-approval clinical trials for finasteride in the 1990s, QuarterWatch said.

Merck manufactures both Propecia and Proscar. The first lawsuits against Merck over Propecia and Proscar were filed in 2011. The federal claims against Merck have been consolidated for multidistrict litigation (MDL) in New York. According to a recent report by the U.S. Judicial Panel for Multidistrict Litigation, there are 139 separate actions currently pending in the Propecia MDL, QuarterWatch said.

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